Females of child-bearing age must use effective contraception (oral progestogen-only contraceptives not considered effective).
Local reactions (such as burning, erythema, stinging, pruritus, dry or peeling skin—discontinue if severe), Drug-induced photosensitivity reactions, acne flare; also reported eye irritation and oedema, changes of skin pigmentation, skin blistering and crusting
Protect your skin from sunlight—even on a bright but cloudy day. Do not use sunbeds.
Avoid abrasive cleaners, astringent cosmetics (such as those containing alcohol), and other preparations to treat acne.
Allow peeling (resulting from other irritant treatments) to subside before using a topical retinoid.
Avoid excessive exposure to sunlight.
May bleach fabrics and hair.